Cancer is caused by mutations in human DNA. Several strands of this type of fat are removed or mixed and the transformation allows the cells to multiply and grow in an unusual way. In some cases, genetic mutations are caused by genetic mutations, inherited and inherited, but in some cases genetic predisposition. Understanding tumor DNA can help develop disease-specific therapies to combat it.
For years, disease education has shown that thyroid cancer it is very common among people exposed to radioactive iodine, especially in people who have been exposed to it in childhood. In high doses, radioactive iodine kills thyroid cells and can be used as treatment thyroid cancer and other thyroid diseases. But the radiation from Chernobyl was not enough to kill the cells. Instead, according to Morton, the proliferation of several months at a slower rate of cellular changes led to tumors.
In his letter, Morton and colleagues were able to examine the tumors of people living near Chernobyl, reading about the DNA of more than 350 people who had thyroid cancer after radiation exposure as young children. He made a complete picture of these tumors. Then, to determine the differences in thyroid cancer caused by other factors, the researchers compared these tumors against the tissue of 81 people who were born near Chernobyl after 1986 and had developed thyroid cancer but had not been exposed to radiation. He also compared the tumors to those of the Cancer Genome Atlas, which has been identified with thousands of cancer genomes.
They found that cancers caused by the breakdown of iodine after melting had changed genes by releasing and breaking down DNA twins. In contrast, thyroid cancer in the Cancer Genome Atlas and in the control group of 81 unidentified individuals in the region may be caused by a single-minded mutation, whereas only one part of DNA is altered.
Following this, scientists inspected several areas near Chernobyl, as well as workers who were assigned to clean and install radioactive materials in the sarcophagus of steel and concrete. Researchers also asked many people about their experiences. For example, isotopes from an electric motor landed in nearby fields and were eaten by cattle grazing, transmitting radiation to their milk and then to people who drank it. As a result many dairy drinks provided insight into the amount of radiation a person has experienced. Astronomers and paramedics worked together to apply these direct and indirect measurements to the re-imagining of radiation that would have been given to those who gave the samples of the disease. “This is a unique situation in which we know a lot about visibility,” says Chanock. “Most genome research studies have no information on where humans came from and what their experiences were.”
This gave researchers the opportunity to see how cancer works. They found that radiation that a person is more familiar with, and at a young age at the time of exposure, DNA explodes significantly.
Finally, the team looked at cancer drivers, genes whose mutations caused a tumor. They found that radiation levels caused by radiation were not significantly different from those observed for thyroid cancer. It was different only for that reason — DNA with two strands — which was different. “That’s what really helped us to understand how radiation causes cancer,” Morton says.
There were no specific biomarkers that claimed that these cells were altered by radiation, which tells scientists that the radiation effect occurred early in the cancer and that the biomarkers – if any – were lost or cleaned as the cancer grew. The similarity in these molecules suggests that these cases do not require new treatment. “These cancers just appear, in the end, like thyroid cancer, so there’s no point in any other treatment,” she says.
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