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Then the pigs came. Yuk joined the team at Mayo Hospital which was large enough to use large animals. The team wanted to avoid relying on natural blood pressure, as many people undergoing surgery have their own side effects. As a result, prior to the test, the three experimental pigs received heparin, which is lower in blood pressure. The researchers cut three holes, 1 centimeter wide and 1 centimeter deep, in each animal’s liver, and then healed the nine injured with a paste or patch of TachoSil.
Tiffany Sarrafian, one of the group’s veterinarians, says she has never seen anything like this glue. “We’re just putting in the paste, and we’re reading” for a few seconds, says Sarrafian, recalling what happened. “You take your hand off and say, ‘Wait, you don’t have any blood!’ It was great fun. ”
Sarrafian planned that if the same demonstration did not work after three minutes, he would change the pesticides to sell the pigs, and allow them to cover and recover naturally. But he did add another element of urgency: he released a small amount of glue. “It’s amazing, in a way,” he says.
In fact, dry patches like TachoSil are not designed to stop heavy blood vessels from infecting animals and from sustained injuries. But, medically, it is an unmet need, says Christoph Nabzdyk, a Mayo team surgeon. “With older people, you have more patients who have anemia or who end up bleeding,” he says. Problems with bleeding, and hemorrhage are important. ”
He and Saraffian add that having a cheap glue that prevents excessive bleeding and moving to a wet area can already save patients, and it may be especially helpful in areas where there is little or no surgical equipment, such as in the desert, in war zones, or in the developed world.
“There is nothing very new in the record, but this idea is good and unacceptable,” says Shrike Zhang, a civil engineer who leads the lab at Harvard Medical School. While materials such as silicone oil and adhesives are common, theirs including they make something fun. “It’s very early, but most of the animals are strong,” he continues.
But according to Wang, the Stanford cardiothoracic resident, there are some things that need to be done before the glue can be used in humans. A glue clip that seals abnormally damaged tissue, or adherence to healthy tissue, can perform any surgical procedures that may follow. “The question is, will you be able to work in this area?” He asks.
Yuk’s team found a way to solve the sticky seal, and the original it brings rats he promises.
They also want to know how long the seal lasts; well, it should not melt until the flesh heals itself, but it must also last forever. This new study shows that the paste dissolves significantly within 12 weeks, taking microscope imaging with different experiments using rats. Depending on the injury and the response to treatment, it can be numerous.
Another problem is that some types of seals are known to kill muscles over time. Wang – and Yuk – know that part-time study is essential. At the moment, their longest interest in blood vessels is taking about a month from the group’s use, using pigs tested at the Mayo Clinic.
And even after so many years have passed since the seal was replaced by a reliable suture, both surgeons and surgeons could still have the potential to grow patients to return quickly, so that the bodies could run again like oil-based machines.
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